United States securities and exchange commission logo February 24, 2021 Jerel Banks Chief Executive Officer Benitec Biopharma Inc. 3940 Trust Way Hayward, CA 94545 Re: Benitec Biopharma Inc. Registration Statement on Form S-3 Filed February 18, 2021 File No. 333-253259 Dear Dr. Banks: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Ada D. Sarmento at 202-551-3798 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Ben D. Orlanski, Esq.