United States securities and exchange commission logo December 14, 2022 Jerel Banks, M.D. Chief Executive Officer Benitec Biopharma Inc. 3940 Trust Way Hayward, California 94545 Re: Benitec Biopharma Inc. Registration Statement on Form S-1 Filed December 13, 2022 File No. 333-268763 Dear Jerel Banks: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tyler Howes at 202-551-3370 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Louis Rambo, Esq.